Sickle Cell Gene Detection Classroom Educational Kit Edvotek
MPN | 989401 |
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Brand | McKesson |
Packaging | EA/1 |
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- To investigate the restriction enzyme that discriminates between hba (normal) and hbs (disease) genes and perform a simulated test on a patient
- Genetically inherited diseases in humans can be caused by a single nucleotide mutation resulting in a change
- Such a substitution can affect the structure and function of a critical protein, rendering it partially or completely nonfunctional
- A classic example is hemoglobin in sickle cell anemia
- Agarose gel-based experiment designed for DNA staining and visualization with InstaStain methylene blue
- Demonstrates the use of a restriction enzyme that discriminates between the normal and sickle cell hemoglobin genes
- This experiment does not contain human DNA
- Requires electrophoresis apparatus, power supply, automatic micropipet and tips, balance, microwave or hot plate, visualization system
- Includes: Instructions, Ready-to-load Quickstrip DNA samples, Ultraspec agarose powder, practice gel loading solution, electrophoresis buffer, Instastain blue and Flashblue